An Inverse Spectral Method to Localize Discordant Alternans Regions on the Heart from Body Surface Measurements
نویسندگان
چکیده
Sudden cardiac death (SCD) is one of the leading causes of death. T-wave alternans (TWA), beat-tobeat alternation in T-wave amplitude, has been shown to be linked to SCD. As risk stratification methods, current TWA detectors still have bad sensitivity. These detectors focus only on the presence of TWA, but not its spatial heterogeneity on the heart , which is thought to be precursors of SCD. We present a method based on the TWA detector Spectral Method (SM) to estimate the spatial distribution of TWA on the heart from body surface measurements. INTRODUCTION
منابع مشابه
Endocardial and epicardial repolarization alternans in human cardiomyopathy: evidence for spatiotemporal heterogeneity and correlation with body surface T-wave alternans.
OBJECTIVES The aim of this study was to define the spatiotemporal distribution of intracardiac alternans and its relationship to body surface alternans in humans. BACKGROUND Spatial heterogeneity of alternans exists in the animal heart owing to nonuniform calcium cycling and restitution kinetics. Patients with cardiomyopathy manifest similar myocardial substrate, which might influence the dis...
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